Input: Over 125 million nucleotides from the genome of 67,280 influenza strains, spanning 100 years and all continents.
Tools: Over 2,500 lines of custom developed computer code in BioPython and online bioinformatics tools such as Clustal/Ω and RAxML.
Output: 1) Antigenicity Prediction Model that supplements Hemagglutinin Inhibition (HI) Assay for predicting the effectiveness of a vaccine.
2) The antigenic drift of the current A/California/07/2009 vaccine.
Please check back, this page is being updated to include recent work
This website is currently tracking the H1N1pdm strain of the influenza virus. Extending the project to other three strains of the quadrivalent vaccine recommended by the World Health Organimzation, namely, H3N2, B/Victoria and B/Yamagata are works-in-progress.
2017-04-20: How does the efficacy of the A/Michigan/45/2015 vaccine strain compare with the emerging Clade 6B.2? More ...
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